MBS item

73332
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In situ hybridization test on breast cancer tissue to determine HER2 gene amplification status for trastuzumab eligibility, requested by a specialist managing the patient's treatment.

Category 6 · Pathology services[Group P7](/groups/P7)

Schedule fee$315.40

100% benefitGP, out of hospital—

85% benefitOut of hospital$268.10

75% benefitIn hospital$236.55

The schedule fee for MBS item 73332 is $315.40. Medicare pays $268.10 (85%) out of hospital, or $236.55 (75%) for a privately admitted patient in hospital. Fee effective 1 January 2013.

Gap for what you charge
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Your fee$

Out of hospitalIn hospital (private)

Medicare pays$268.10

Patient gap$47.30

Bulk billing means accepting $268.10 as full payment, with no gap and no extra charges. [Add incentives](/bulk-billing?item=73332)

Item descriptor
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An in situ hybridization (ISH) test of tumour tissue from a patient with breast cancer requested by, or on the advice of, a specialist or consultant physician who manages the treatment of the patient to determine if the requirements relating to human epidermal growth factor receptor 2 (HER2) gene amplification for access to trastuzumab under the Pharmaceutical Benefits Scheme (PBS) or the Herceptin Program are fulfilled.

[Explanatory notes and rules on MBS Online ↗](https://www9.health.gov.au/mbs/fullDisplay.cfm?type=item&q=73332)

Health fund and DVA rates
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Total fee each scheme recognises for this item in hospital.

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Guides
------

- [How Medicare benefits work: schedule fees, 75%, 85% and 100%](/guides/how-medicare-benefits-work)
- [Medicare safety nets explained: original and extended (EMSN) thresholds for 2026](/guides/medicare-safety-nets)
- [In-hospital billing: the 75% benefit, the 25% fund benefit, and no-gap and known-gap schemes](/guides/in-hospital-billing-and-gap-cover)
- [Bulk billing incentives and BBPIP explained: 2026 amounts by MM area](/guides/bulk-billing-incentives)
- [The MBS multiple operation rule and surgical assistant fees](/guides/multiple-operation-rule)
- [Assignment of benefit for bulk billing: the changes from 1 July 2026](/guides/assignment-of-benefit-2026)
- [MBS telehealth rules: the eligible telehealth practitioner and phone items](/guides/mbs-telehealth-rules)
- [GP chronic condition management plans: items 965 and 967 explained](/guides/chronic-condition-management-plans)
- [Medicare billing compliance: claim time limits, records and the 80/20 rule](/guides/medicare-billing-compliance)

Data source: [Australian Government Medicare Benefits Schedule](https://www.mbsonline.gov.au/) · Record updated 1 September 2026. Health fund rates come from each fund's published schedule. Verify item descriptors, rules and fees on [MBS Online](https://www9.health.gov.au/mbs/fullDisplay.cfm?type=item&q=73332) before billing. This is a reference tool, not billing or financial advice.